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Discovery of 4-Phenylpiperidine-2-Carboxamide Analogues as Serotonin 5-HT2C Receptor-Positive Allosteric Modulators with Enhanced Drug-like Properties.
Wold, Eric A; Garcia, Erik J; Wild, Christopher T; Miszkiel, Joanna M; Soto, Claudia A; Chen, Jianping; Pazdrak, Konrad; Fox, Robert G; Anastasio, Noelle C; Cunningham, Kathryn A; Zhou, Jia.
Afiliação
  • Wold EA; Center for Addiction Research, University of Texas Medical Branch, Galveston, Texas 77555, United States.
  • Garcia EJ; Chemical Biology Program and the Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555, United States.
  • Wild CT; Center for Addiction Research, University of Texas Medical Branch, Galveston, Texas 77555, United States.
  • Miszkiel JM; Center for Addiction Research, University of Texas Medical Branch, Galveston, Texas 77555, United States.
  • Soto CA; Chemical Biology Program and the Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555, United States.
  • Chen J; Center for Addiction Research, University of Texas Medical Branch, Galveston, Texas 77555, United States.
  • Pazdrak K; Center for Addiction Research, University of Texas Medical Branch, Galveston, Texas 77555, United States.
  • Fox RG; Center for Addiction Research, University of Texas Medical Branch, Galveston, Texas 77555, United States.
  • Anastasio NC; Chemical Biology Program and the Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555, United States.
  • Cunningham KA; Center for Addiction Research, University of Texas Medical Branch, Galveston, Texas 77555, United States.
  • Zhou J; Center for Addiction Research, University of Texas Medical Branch, Galveston, Texas 77555, United States.
J Med Chem ; 63(14): 7529-7544, 2020 07 23.
Article em En | MEDLINE | ID: mdl-32567857
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperidinas / Receptor 5-HT2C de Serotonina / Agonistas do Receptor 5-HT2 de Serotonina Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperidinas / Receptor 5-HT2C de Serotonina / Agonistas do Receptor 5-HT2 de Serotonina Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article