Impact of high tidal volume ventilation on surfactant metabolism and lung injury in infant rats.

Wiegert, Susanne; Greco, Francesco; Baumann, Philipp; Wellmann, Sven; Grest, Paula; Hetzel, Udo; Cannizzaro, Vincenzo

Wiegert, Susanne; Greco, Francesco; Baumann, Philipp; Wellmann, Sven; Grest, Paula; Hetzel, Udo; Cannizzaro, Vincenzo.

Afiliação

Wiegert S; Department of Intensive Care Medicine and Neonatology, University Children's Hospital Zurich, Zurich, Switzerland.
Greco F; Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland.
Baumann P; Zurich Centre for Integrative Human Physiology, Zurich, Switzerland.
Wellmann S; Department of Intensive Care Medicine and Neonatology, University Children's Hospital Zurich, Zurich, Switzerland.
Grest P; Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland.
Hetzel U; Zurich Centre for Integrative Human Physiology, Zurich, Switzerland.
Cannizzaro V; Department of Intensive Care Medicine and Neonatology, University Children's Hospital Zurich, Zurich, Switzerland.

Am J Physiol Lung Cell Mol Physiol ; 319(3): L562-L575, 2020 09 01.

Article em En | MEDLINE | ID: mdl-32579393

Assuntos

Lesão Pulmonar/metabolismo; Lesão Pulmonar/fisiopatologia; Surfactantes Pulmonares/metabolismo; Volume de Ventilação Pulmonar/fisiologia; Animais; Líquido da Lavagem Broncoalveolar/citologia; Pulmão/metabolismo; Pulmão/fisiopatologia; Ratos; Mecânica Respiratória/fisiologia; Tensoativos/metabolismo

Palavras-chave

animal model; electron microscopy; respiratory system mechanics; surfactant metabolism; ventilator-induced lung injury

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Surfactantes Pulmonares / Volume de Ventilação Pulmonar / Lesão Pulmonar Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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