Programmed death ligand 1 protein expression, histological tumour differentiation and intratumoural heterogeneity in pulmonary adenocarcinoma.

Tancos, Vladimír; Grendár, Marián; Farkasová, Anna; Hutka, Zdenko; Micák, Jozef; Kviatkovská, Zuzana; Hardman, Timothy C; Hardy, Gareth A D; Plank, Lukás

Tancos, Vladimír; Grendár, Marián; Farkasová, Anna; Hutka, Zdenko; Micák, Jozef; Kviatkovská, Zuzana; Hardman, Timothy C; Hardy, Gareth A D; Plank, Lukás.

Afiliação

Tancos V; Department of Pathological Anatomy, Comenius University in Bratislava, Jessenius Faculty of Medicine and University Hospital in Martin, Slovakia. Electronic address: tancos1@uniba.sk.
Grendár M; Department of Bioinformatics, Biomedical Centre Martin, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Slovakia.
Farkasová A; Martin's Biopsy Centre Ltd, Martin, Slovakia.
Hutka Z; Department of Pathological Anatomy, Comenius University in Bratislava, Jessenius Faculty of Medicine and University Hospital in Martin, Slovakia.
Micák J; Department of Pathological Anatomy, Comenius University in Bratislava, Jessenius Faculty of Medicine and University Hospital in Martin, Slovakia.
Kviatkovská Z; Martin's Biopsy Centre Ltd, Martin, Slovakia.
Hardman TC; Niche Science and Technology Ltd, London, UK.
Hardy GAD; Niche Science and Technology Ltd, London, UK.
Plank L; Department of Pathological Anatomy, Comenius University in Bratislava, Jessenius Faculty of Medicine and University Hospital in Martin, Slovakia; Martin's Biopsy Centre Ltd, Martin, Slovakia.

Pathology ; 52(5): 538-545, 2020 Aug.

Article em En | MEDLINE | ID: mdl-32586689

Assuntos

Adenocarcinoma de Pulmão/metabolismo; Antígeno B7-H1/metabolismo; Regulação Neoplásica da Expressão Gênica; Neoplasias Pulmonares/metabolismo; Pulmão/metabolismo; Adenocarcinoma de Pulmão/patologia; Antígeno B7-H1/genética; Humanos; Pulmão/patologia; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/patologia; Estudos Retrospectivos

Palavras-chave

Programmed death ligand 1; immunotherapy; intratumoural heterogeneity; non-small cell lung cancer

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Antígeno B7-H1 / Adenocarcinoma de Pulmão / Pulmão / Neoplasias Pulmonares Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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