Probability of mycobactericidal activity of para-aminosalicylic acid with novel dosing regimens.

Abulfathi, Ahmed A; Assawasuwannakit, Piyanan; Donald, Peter R; Diacon, Andreas H; Reuter, Helmuth; Svensson, Elin M

Abulfathi, Ahmed A; Assawasuwannakit, Piyanan; Donald, Peter R; Diacon, Andreas H; Reuter, Helmuth; Svensson, Elin M.

Afiliação

Abulfathi AA; Division of Clinical Pharmacology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa. aaabulfathi@sun.ac.za.
Assawasuwannakit P; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.
Donald PR; Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Diacon AH; Task Applied Science, Bellville, South Africa.
Reuter H; Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Svensson EM; Division of Clinical Pharmacology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Eur J Clin Pharmacol ; 76(11): 1557-1565, 2020 Nov.

Article em En | MEDLINE | ID: mdl-32588106

Assuntos

Ácido Aminossalicílico/administração & dosagem; Antituberculosos/administração & dosagem; Tuberculose Resistente a Múltiplos Medicamentos/tratamento farmacológico; Ácido Aminossalicílico/farmacocinética; Esquema de Medicação; Humanos; Testes de Sensibilidade Microbiana; Modelos Biológicos; Probabilidade

Palavras-chave

Modelling; PK/PD; Para-aminosalicylic acid; Pharmacokinetics; Tuberculosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Aminossalicílico / Tuberculose Resistente a Múltiplos Medicamentos / Antituberculosos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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