Novel evidence for oncogenic piRNA-823 as a promising prognostic biomarker and a potential therapeutic target in colorectal cancer.

Feng, Junlan; Yang, Muqing; Wei, Qing; Song, Feifei; Zhang, Youhua; Wang, Xiaodong; Liu, Bin; Li, Jiyu

Feng, Junlan; Yang, Muqing; Wei, Qing; Song, Feifei; Zhang, Youhua; Wang, Xiaodong; Liu, Bin; Li, Jiyu.

Afiliação

Feng J; Department of General Surgery, School of Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Yang M; Department of General Surgery, School of Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Wei Q; Department of Pathology, School of Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Song F; Department of Pathology, School of Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Zhang Y; Department of Pathology, School of Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Wang X; Department of General Surgery, School of Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Liu B; Department of General Surgery, School of Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Li J; Department of General Surgery, School of Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.

J Cell Mol Med ; 24(16): 9028-9040, 2020 08.

Article em En | MEDLINE | ID: mdl-32596991

Assuntos

Biomarcadores Tumorais/genética; Neoplasias Colorretais/genética; Oncogenes/genética; RNA Interferente Pequeno/genética; Apoptose/genética; Linhagem Celular; Linhagem Celular Tumoral; Proliferação de Células/genética; Neoplasias Colorretais/patologia; Regulação Neoplásica da Expressão Gênica/genética; Células HCT116; Células HEK293; Humanos; Subunidade alfa do Fator 1 Induzível por Hipóxia/genética; Prognóstico; Espécies Reativas de Oxigênio/metabolismo; Transdução de Sinais/genética; Regulação para Cima/genética

Palavras-chave

G6PD; HIF-1α; colorectal cancer; glucose consumption; piRNA-823

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oncogenes / Neoplasias Colorretais / Biomarcadores Tumorais / RNA Interferente Pequeno Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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