High-resolution peripheral quantitative computed tomography in children with osteogenesis imperfecta.
Pediatr Radiol
; 50(12): 1781-1787, 2020 11.
Article
em En
| MEDLINE
| ID: mdl-32613359
ABSTRACT
Bone health in children with osteogenesis imperfecta is monitored using radiographs and dual-energy X-ray absorptiometry, which have limitations. High-resolution peripheral quantitative CT can non-invasively derive bone microarchitectural data. Children with severe osteogenesis imperfecta have fragile deformed bones, and positioning for this scan can be difficult. We assessed the feasibility of high-resolution peripheral quantitative CT in nine children aged 9-15 years with osteogenesis imperfecta and compared results with dual-energy X-ray absorptiometry and with healthy controls. All nine recruited children were successfully scanned and showed no preference for either modality. It therefore appears feasible to perform high-resolution peripheral quantitative CT in children with osteogenesis imperfecta aged 9 years and older. Future studies should focus on understanding the clinical implications of the technology in this patient cohort.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Osteogênese Imperfeita
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Interpretação de Imagem Radiográfica Assistida por Computador
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Tomografia Computadorizada por Raios X
Limite:
Adolescent
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Child
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article