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LC-MS/MS method for quantitation of the CK2 inhibitor silmitasertib (CX-4945) in human plasma, CSF, and brain tissue, and application to a clinical pharmacokinetic study in children with brain tumors.
Zhong, Bo; Campagne, Olivia; Salloum, Ralph; Purzner, Teresa; Stewart, Clinton F.
Afiliação
  • Zhong B; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, United States.
  • Campagne O; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, United States.
  • Salloum R; Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.
  • Purzner T; Stanford University School of Medicine, Stanford, CA, United States.
  • Stewart CF; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, United States. Electronic address: clinton.stewart@stjude.org.
J Chromatogr B Analyt Technol Biomed Life Sci ; 1152: 122254, 2020 Sep 01.
Article em En | MEDLINE | ID: mdl-32615532
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenazinas / Neoplasias Encefálicas / Espectrometria de Massas em Tandem / Cromatografia de Fase Reversa / Naftiridinas / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Child / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenazinas / Neoplasias Encefálicas / Espectrometria de Massas em Tandem / Cromatografia de Fase Reversa / Naftiridinas / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Child / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article