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Drug-Drug Interaction Risk Assessment of Esaxerenone as a Perpetrator by In Vitro Studies and Static and Physiologically Based Pharmacokinetic Models.
Yamada, Makiko; Ishizuka, Tomoko; Inoue, Shin-Ichi; Rozehnal, Veronika; Fischer, Thomas; Sugiyama, Daisuke.
Afiliação
  • Yamada M; Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan (M.Y., T.I., S.I., D.S.) and Tissue and Cell Research Center Munich, Daiichi Sankyo Europe GmbH, Martinsried, Germany (V.R., T.F.) yamada.makiko.jr@daiichisankyo.co.jp.
  • Ishizuka T; Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan (M.Y., T.I., S.I., D.S.) and Tissue and Cell Research Center Munich, Daiichi Sankyo Europe GmbH, Martinsried, Germany (V.R., T.F.).
  • Inoue SI; Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan (M.Y., T.I., S.I., D.S.) and Tissue and Cell Research Center Munich, Daiichi Sankyo Europe GmbH, Martinsried, Germany (V.R., T.F.).
  • Rozehnal V; Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan (M.Y., T.I., S.I., D.S.) and Tissue and Cell Research Center Munich, Daiichi Sankyo Europe GmbH, Martinsried, Germany (V.R., T.F.).
  • Fischer T; Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan (M.Y., T.I., S.I., D.S.) and Tissue and Cell Research Center Munich, Daiichi Sankyo Europe GmbH, Martinsried, Germany (V.R., T.F.).
  • Sugiyama D; Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan (M.Y., T.I., S.I., D.S.) and Tissue and Cell Research Center Munich, Daiichi Sankyo Europe GmbH, Martinsried, Germany (V.R., T.F.).
Drug Metab Dispos ; 48(9): 769-777, 2020 09.
Article em En | MEDLINE | ID: mdl-32616542
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirróis / Sulfonas / Antagonistas de Receptores de Mineralocorticoides / Indutores do Citocromo P-450 CYP3A / Inibidores do Citocromo P-450 CYP3A / Modelos Biológicos Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Male País como assunto: Asia Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirróis / Sulfonas / Antagonistas de Receptores de Mineralocorticoides / Indutores do Citocromo P-450 CYP3A / Inibidores do Citocromo P-450 CYP3A / Modelos Biológicos Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Male País como assunto: Asia Idioma: En Ano de publicação: 2020 Tipo de documento: Article