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Neutralization of HSF1 in cells from PIK3CA-related overgrowth spectrum patients blocks abnormal proliferation.
Da Costa, Romain; De Almeida, Steven; Chevarin, Martin; Hadj-Rabia, Smail; Leclerc-Mercier, Stéphanie; Thauvin-Robinet, Christel; Garrido, Carmen; Faivre, Laurence; Vabres, Pierre; Duplomb, Laurence; Jego, Gaëtan.
Afiliação
  • Da Costa R; INSERM, LNC UMR1231, Team GAD, University of Burgundy and Franche-Comté, F-21000, Dijon, France; FHU-TRANSLAD, University of Burgundy and Franche-Comté, Dijon University Hospital, F-21000, Dijon, France.
  • De Almeida S; INSERM, LNC UMR1231 Team HSP-pathies, University of Burgundy and Franche-Comté, F-21000, Dijon, France.
  • Chevarin M; INSERM, LNC UMR1231, Team GAD, University of Burgundy and Franche-Comté, F-21000, Dijon, France; FHU-TRANSLAD, University of Burgundy and Franche-Comté, Dijon University Hospital, F-21000, Dijon, France.
  • Hadj-Rabia S; Department of Dermatology, Reference Center for Genodermatoses and Rare Skin Diseases (MAGEC), Hôpital Universitaire Necker- Enfants Malades, Assistance Publique - Hôpitaux de Paris-Centre (AP-HP5), Paris, France.
  • Leclerc-Mercier S; Department of Pathology, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.
  • Thauvin-Robinet C; INSERM, LNC UMR1231, Team GAD, University of Burgundy and Franche-Comté, F-21000, Dijon, France; FHU-TRANSLAD, University of Burgundy and Franche-Comté, Dijon University Hospital, F-21000, Dijon, France.
  • Garrido C; INSERM, LNC UMR1231 Team HSP-pathies, University of Burgundy and Franche-Comté, F-21000, Dijon, France.
  • Faivre L; INSERM, LNC UMR1231, Team GAD, University of Burgundy and Franche-Comté, F-21000, Dijon, France; FHU-TRANSLAD, University of Burgundy and Franche-Comté, Dijon University Hospital, F-21000, Dijon, France.
  • Vabres P; INSERM, LNC UMR1231, Team GAD, University of Burgundy and Franche-Comté, F-21000, Dijon, France; FHU-TRANSLAD, University of Burgundy and Franche-Comté, Dijon University Hospital, F-21000, Dijon, France; Department of Dermatology, Dijon University Hospital, F-21000, Dijon, France.
  • Duplomb L; INSERM, LNC UMR1231, Team GAD, University of Burgundy and Franche-Comté, F-21000, Dijon, France; FHU-TRANSLAD, University of Burgundy and Franche-Comté, Dijon University Hospital, F-21000, Dijon, France.
  • Jego G; INSERM, LNC UMR1231 Team HSP-pathies, University of Burgundy and Franche-Comté, F-21000, Dijon, France. Electronic address: gaetan.jego@u-bourgogne.fr.
Biochem Biophys Res Commun ; 530(3): 520-526, 2020 09 24.
Article em En | MEDLINE | ID: mdl-32620236
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proliferação de Células / Malformações Vasculares / Descoberta de Drogas / Classe I de Fosfatidilinositol 3-Quinases / Fatores de Transcrição de Choque Térmico / Lipoma / Anormalidades Musculoesqueléticas / Nevo Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proliferação de Células / Malformações Vasculares / Descoberta de Drogas / Classe I de Fosfatidilinositol 3-Quinases / Fatores de Transcrição de Choque Térmico / Lipoma / Anormalidades Musculoesqueléticas / Nevo Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article