Resolution of pembrolizumab-associated lichenoid dermatitis with a single dose of methotrexate.
Dermatol Online J
; 26(5)2020 May 15.
Article
em En
| MEDLINE
| ID: mdl-32621697
ABSTRACT
We present a 53-year-old woman with severe lichenoid dermatitis secondary to pembrolizumab therapy that was refractory to both topical and oral steroids. After almost three months without improvement, the rash was effectively combated with a single 15mg dose of methotrexate. We hope this case will help guide the management of the cutaneous adverse effects of anti-PD1 immunotherapy.
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Base de dados:
MEDLINE
Assunto principal:
Metotrexato
/
Erupções Liquenoides
/
Anticorpos Monoclonais Humanizados
/
Antineoplásicos Imunológicos
/
Imunossupressores
Tipo de estudo:
Risk_factors_studies
Limite:
Female
/
Humans
/
Middle aged
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article