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Synthesis and structure activity relationships of cyanopyridone based anti-tuberculosis agents.
Jian, Yanlin; Hulpia, Fabian; Risseeuw, Martijn D P; Forbes, He Eun; Munier-Lehmann, Hélène; Caljon, Guy; Boshoff, Helena I M; Van Calenbergh, Serge.
Afiliação
  • Jian Y; Laboratory for Medicinal Chemistry (FFW), Ghent University, Ottergemsesteenweg 460, B9000, Gent, Belgium.
  • Hulpia F; Laboratory for Medicinal Chemistry (FFW), Ghent University, Ottergemsesteenweg 460, B9000, Gent, Belgium.
  • Risseeuw MDP; Laboratory for Medicinal Chemistry (FFW), Ghent University, Ottergemsesteenweg 460, B9000, Gent, Belgium.
  • Forbes HE; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, 20892, United States.
  • Munier-Lehmann H; Unit of Chemistry and Biocatalysis, Department of Structural Biology and Chemistry, Institut Pasteur, CNRS UMR3523, 28 Rue du Dr. Roux, Cedex 15, 75724, Paris, France.
  • Caljon G; Laboratory of Microbiology, Parasitology and Hygiene, University of Antwerp, Universiteitsplein 1(S7), B2610, Wilrijk, Belgium.
  • Boshoff HIM; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, 20892, United States.
  • Van Calenbergh S; Laboratory for Medicinal Chemistry (FFW), Ghent University, Ottergemsesteenweg 460, B9000, Gent, Belgium. Electronic address: serge.vancalenbergh@ugent.be.
Eur J Med Chem ; 201: 112450, 2020 Sep 01.
Article em En | MEDLINE | ID: mdl-32623208
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridonas / Proteínas de Bactérias / Núcleosídeo-Fosfato Quinase / Inibidores Enzimáticos / Nitrilas / Antituberculosos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridonas / Proteínas de Bactérias / Núcleosídeo-Fosfato Quinase / Inibidores Enzimáticos / Nitrilas / Antituberculosos Idioma: En Ano de publicação: 2020 Tipo de documento: Article