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A novel pipeline of 2-(benzenesulfonamide)-N-(4-hydroxyphenyl) acetamide analgesics that lack hepatotoxicity and retain antipyresis.
Bazan, Hernan A; Bhattacharjee, Surjyadipta; Burgos, Carolina; Recio, Javier; Abet, Valentina; Pahng, Amanda R; Jun, Bokkyoo; Heap, Jessica; Ledet, Alexander J; Gordon, William C; Edwards, Scott; Paul, Dennis; Alvarez-Builla, Julio; Bazan, Nicolas G.
Afiliação
  • Bazan HA; Section of Vascular/Endovascular Surgery, Department of Surgery, Ochsner Clinic, New Orleans, LA, 70118, USA. Electronic address: hbazan@ochsner.org.
  • Bhattacharjee S; Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, 70112, USA.
  • Burgos C; Department of Organic Chemistry and IQAR, University of Alcala, Alcala de Henares, Madrid, 28805, Spain.
  • Recio J; Department of Organic Chemistry and IQAR, University of Alcala, Alcala de Henares, Madrid, 28805, Spain.
  • Abet V; Department of Organic Chemistry and IQAR, University of Alcala, Alcala de Henares, Madrid, 28805, Spain.
  • Pahng AR; Department of Physiology, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, 70112, USA; Southeast Louisiana Veterans Health Care System, New Orleans, LA, 70119, USA.
  • Jun B; Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, 70112, USA.
  • Heap J; Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, 70112, USA.
  • Ledet AJ; Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, 70112, USA.
  • Gordon WC; Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, 70112, USA.
  • Edwards S; Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, 70112, USA; Department of Physiology, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, 70112, USA.
  • Paul D; Department of Pharmacology and Experimental Therapeutics, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, 70112, USA.
  • Alvarez-Builla J; Department of Organic Chemistry and IQAR, University of Alcala, Alcala de Henares, Madrid, 28805, Spain.
  • Bazan NG; Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, 70112, USA.
Eur J Med Chem ; 202: 112600, 2020 Sep 15.
Article em En | MEDLINE | ID: mdl-32629335
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença Hepática Induzida por Substâncias e Drogas / Antipiréticos / Hipertermia / Analgésicos / Fígado / Acetamidas Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença Hepática Induzida por Substâncias e Drogas / Antipiréticos / Hipertermia / Analgésicos / Fígado / Acetamidas Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article