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ß-amyloid and tau drive early Alzheimer's disease decline while glucose hypometabolism drives late decline.
Hammond, Tyler C; Xing, Xin; Wang, Chris; Ma, David; Nho, Kwangsik; Crane, Paul K; Elahi, Fanny; Ziegler, David A; Liang, Gongbo; Cheng, Qiang; Yanckello, Lucille M; Jacobs, Nathan; Lin, Ai-Ling.
Afiliação
  • Hammond TC; Sanders-Brown Center on Aging, University of Kentucky, 307 Sanders-Brown Building, 800 S. Limestone Street, Lexington, KY, 40506-0230, USA.
  • Xing X; Department of Neuroscience, University of Kentucky, Lexington, KY, USA.
  • Wang C; Sanders-Brown Center on Aging, University of Kentucky, 307 Sanders-Brown Building, 800 S. Limestone Street, Lexington, KY, 40506-0230, USA.
  • Ma D; Department of Computer Science, University of Kentucky, Lexington, KY, USA.
  • Nho K; Department of Computer Science, University of Kentucky, Lexington, KY, USA.
  • Crane PK; Sanders-Brown Center on Aging, University of Kentucky, 307 Sanders-Brown Building, 800 S. Limestone Street, Lexington, KY, 40506-0230, USA.
  • Elahi F; Department of Statistics, Harvard University, Boston, MA, USA.
  • Ziegler DA; Department of Radiology and Imaging Sciences, Indiana Alzheimer Disease Center, Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Liang G; Department of Medicine, University of Washington, Seattle, WA, USA.
  • Cheng Q; Department of Neurology, University of California, San Francisco, CA, USA.
  • Yanckello LM; Department of Neurology, University of California, San Francisco, CA, USA.
  • Jacobs N; Department of Computer Science, University of Kentucky, Lexington, KY, USA.
  • Lin AL; Institute of Biomedical Informatics, University of Kentucky, Lexington, KY, USA.
Commun Biol ; 3(1): 352, 2020 07 06.
Article em En | MEDLINE | ID: mdl-32632135

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Proteínas tau / Doença de Alzheimer / Glucose Tipo de estudo: Prognostic_studies Limite: Aged / Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Proteínas tau / Doença de Alzheimer / Glucose Tipo de estudo: Prognostic_studies Limite: Aged / Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article