The impact of pre-existing HLA and red blood cell antibodies on transfusion support and engraftment in sickle cell disease after nonmyeloablative hematopoietic stem cell transplantation from HLA-matched sibling donors: A prospective, single-center, observational study.

Nickel, Robert Sheppard; Flegel, Willy A; Adams, Sharon D; Hendrickson, Jeanne E; Liang, Hua; Tisdale, John F; Hsieh, Matthew M

Nickel, Robert Sheppard; Flegel, Willy A; Adams, Sharon D; Hendrickson, Jeanne E; Liang, Hua; Tisdale, John F; Hsieh, Matthew M.

Afiliação

Nickel RS; Children's National Hospital, Division of Hematology, 111 Michigan Ave NW, Washington, DC 20010, United States.
Flegel WA; The George Washington University School of Medicine and Health Sciences, Washington, DC, United States.
Adams SD; Department of Transfusion Medicine, NIH Clinical Center, National Institutes of Health, Bethesda, MD, United States.
Hendrickson JE; Department of Transfusion Medicine, NIH Clinical Center, National Institutes of Health, Bethesda, MD, United States.
Liang H; Departments of Laboratory Medicine and Pediatrics, Yale School of Medicine, New Haven, CT, United States.
Tisdale JF; The George Washington University, Department of Statistics, Washington, DC, United States.
Hsieh MM; Cellular and Molecular Therapeutics Branch, National Institutes of Health, Bethesda, MD, United States.

EClinicalMedicine ; 24: 100432, 2020 Jul.

Article em En | MEDLINE | ID: mdl-32637902

Palavras-chave

Alloimmunization; Bone marrow transplant; Chimerism; GVHD, graft-versus-host disease; HLA antibody; HLA, human leukocyte antigen; HSCT, hematopoietic stem cell transplantation; NHLBI, National Heart, Lung, and Blood Institute; NIH, National Institutes of Health; RBC, red blood cell; SCD, sickle cell disease; Sickle cell disease; Transfusion

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Observational_studies / Risk_factors_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Observational_studies / Risk_factors_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article