Presynaptic Homeostatic Plasticity Staves off Neurodegenerative Pathophysiology up to a Tipping Point.
Neuron
; 107(1): 6-8, 2020 07 08.
Article
em En
| MEDLINE
| ID: mdl-32645308
ABSTRACT
In this issue of Neuron, Orr et al. (2020) identify an evolutionarily conserved mechanism of presynaptic homeostatic plasticity induced by ALS-like motor neuron degeneration, which maintains excitatory potentials until a threshold of synaptic loss is reached. Past this tipping point, disease onset progresses rapidly.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neuroproteção
/
Plasticidade Neuronal
Limite:
Animals
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article