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LRP1 knockdown aggravates Aß1-42-stimulated microglial and astrocytic neuroinflammatory responses by modulating TLR4/NF-κB/MAPKs signaling pathways.
He, Yingying; Ruganzu, John Bosco; Jin, Hui; Peng, Xiaoqian; Ji, Shengfeng; Ma, Yanbing; Zheng, Liming; Yang, Weina.
Afiliação
  • He Y; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, Shaanxi, China.
  • Ruganzu JB; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, Shaanxi, China.
  • Jin H; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, Shaanxi, China.
  • Peng X; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, Shaanxi, China.
  • Ji S; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, Shaanxi, China.
  • Ma Y; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, Shaanxi, China.
  • Zheng L; Basic Medical Experimental Teaching Center, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, Shaanxi, China.
  • Yang W; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, Shaanxi, China. Electronic address: wn_yang@mail.xjtu.edu.cn.
Exp Cell Res ; 394(2): 112166, 2020 09 15.
Article em En | MEDLINE | ID: mdl-32645395
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Astrócitos / Peptídeos beta-Amiloides / NF-kappa B / Microglia / Sistema de Sinalização das MAP Quinases / Proteína-1 Relacionada a Receptor de Lipoproteína de Baixa Densidade / Receptor 4 Toll-Like / Inflamação Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Astrócitos / Peptídeos beta-Amiloides / NF-kappa B / Microglia / Sistema de Sinalização das MAP Quinases / Proteína-1 Relacionada a Receptor de Lipoproteína de Baixa Densidade / Receptor 4 Toll-Like / Inflamação Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article