Identification of in vitro phase I metabolites of benzotriazole UV stabilizer UV-327 using HPLC coupled with mass spectrometry.

Fischer, Corinna; Leibold, Edgar; Göen, Thomas

Fischer, Corinna; Leibold, Edgar; Göen, Thomas.

Afiliação

Fischer C; Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg, Henkestraße 9-11, 91054 Erlangen, Germany.
Leibold E; BASF SE, Product Safety, Carl-Bosch-Straße 38, 67056 Ludwigshafen am Rhein, Germany.
Göen T; Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg, Henkestraße 9-11, 91054 Erlangen, Germany. Electronic address: thomas.goeen@fau.de.

Toxicol In Vitro ; 68: 104932, 2020 Oct.

Article em En | MEDLINE | ID: mdl-32652170

Assuntos

Triazóis/metabolismo; Biotransformação; Cromatografia Líquida de Alta Pressão; Humanos; Espectrometria de Massas; Microssomos Hepáticos/metabolismo; Raios Ultravioleta

Palavras-chave

Benzotriazole UV stabilizer; Human liver microsomes; In vitro metabolism; Phase I biotransformation; UV-327

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triazóis Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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