Enzymatically stable analogue of the gut-derived peptide xenin on beta-cell transdifferentiation in high fat fed and insulin-deficient Ins1<sup>Cre/+</sup> ;Rosa26-eYFP mice.

Tanday, Neil; Moffett, R Charlotte; Gault, Victor A; Flatt, Peter R; Irwin, Nigel

Enzymatically stable analogue of the gut-derived peptide xenin on beta-cell transdifferentiation in high fat fed and insulin-deficient Ins1^Cre/+ ;Rosa26-eYFP mice.

Tanday, Neil; Moffett, R Charlotte; Gault, Victor A; Flatt, Peter R; Irwin, Nigel.

Afiliação

Tanday N; SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, UK.
Moffett RC; SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, UK.
Gault VA; SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, UK.
Flatt PR; SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, UK.
Irwin N; SAAD Centre for Pharmacy and Diabetes, Ulster University, Coleraine, Northern Ireland, UK.

Diabetes Metab Res Rev ; 37(3): e3384, 2021 03.

Article em En | MEDLINE | ID: mdl-32662136

Assuntos

Transdiferenciação Celular; Diabetes Mellitus Experimental; Células Secretoras de Insulina; Neurotensina; Animais; Diabetes Mellitus Experimental/metabolismo; Gorduras na Dieta/administração & dosagem; Células Secretoras de Insulina/fisiologia; Camundongos; Camundongos Transgênicos; Neurotensina/metabolismo

Palavras-chave

Ins1Cre/+;Rosa26-eYFP mice; beta-cell dedifferentiation; high fat fed; islet; streptozotocin; xenin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neurotensina / Diabetes Mellitus Experimental / Células Secretoras de Insulina / Transdiferenciação Celular Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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