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Immunocyte single cell analysis of vaccine-induced narcolepsy.
Lind, Alexander; Salami, Falastin; Landtblom, Anne-Marie; Palm, Lars; Lernmark, Åke; Adolfsson, Jörgen; Elding Larsson, Helena.
Afiliação
  • Lind A; Department of Clinical Sciences, Lund University/Clinical Research Center (CRC), Skåne University Hospital SUS, Malmö, 21430, Sweden.
  • Salami F; Department of Clinical Sciences, Lund University/Clinical Research Center (CRC), Skåne University Hospital SUS, Malmö, 21430, Sweden.
  • Landtblom AM; Department of Neuroscience, Uppsala University, Uppsala, 75124, Sweden.
  • Palm L; Department of Clinical Sciences, Lund University/Clinical Research Center (CRC), Skåne University Hospital SUS, Malmö, 21430, Sweden.
  • Lernmark Å; Department of Clinical Sciences, Lund University/Clinical Research Center (CRC), Skåne University Hospital SUS, Malmö, 21430, Sweden.
  • Adolfsson J; Science for Life Laboratory node, Linköping University, Linköping, 58183, Sweden.
  • Elding Larsson H; Department of Clinical Sciences, Lund University/Clinical Research Center (CRC), Skåne University Hospital SUS, Malmö, 21430, Sweden.
Eur J Immunol ; 51(1): 247-249, 2021 01.
Article em En | MEDLINE | ID: mdl-32671842
ABSTRACT
Increased incidence of narcolepsy type 1 (NT1) was observed following Pandemrix®-vaccination, initiated as a preventive measure against the 2009 Influenza pandemic. Here, single cell analysis was conducted to suggest a lower number of CD8+ CD27+ T cells among these patients. These findings provide understanding into the autoimmune pathogenesis of NT1.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vacinas contra Influenza / Narcolepsia Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vacinas contra Influenza / Narcolepsia Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article