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ADAM15 expression is increased in lung CD8+ T cells, macrophages, and bronchial epithelial cells in patients with COPD and is inversely related to airflow obstruction.
Wang, Xiaoyun; Zhang, Duo; Higham, Andrew; Wolosianka, Sophie; Gai, Xiaoyan; Zhou, Lu; Petersen, Hans; Pinto-Plata, Victor; Divo, Miguel; Silverman, Edwin K; Celli, Bartolome; Singh, Dave; Sun, Yongchang; Owen, Caroline A.
Afiliação
  • Wang X; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
  • Zhang D; Program in Clinical and Experimental Therapeutics, Department of Clinical and Administrative Pharmacy, College of Pharmacy, University of Georgia, Augusta, GA, 30901, USA.
  • Higham A; Vascular Biology Center, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA.
  • Wolosianka S; Medicines Evaluation Unit, University of Manchester, Manchester University NHS Foundation Trust, Manchester, UK.
  • Gai X; Medicines Evaluation Unit, University of Manchester, Manchester University NHS Foundation Trust, Manchester, UK.
  • Zhou L; Department of Pulmonary and Critical Care Medicine, Peking University Third Hospital, Beijing, China.
  • Petersen H; Department of Pulmonary and Critical Care Medicine, Peking University Third Hospital, Beijing, China.
  • Pinto-Plata V; The Lovelace Respiratory Research Institute, Albuquerque, NM, 87108, USA.
  • Divo M; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
  • Silverman EK; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
  • Celli B; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
  • Singh D; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
  • Sun Y; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
  • Owen CA; Medicines Evaluation Unit, University of Manchester, Manchester University NHS Foundation Trust, Manchester, UK.
Respir Res ; 21(1): 188, 2020 Jul 16.
Article em En | MEDLINE | ID: mdl-32677970

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Brônquios / Macrófagos Alveolares / Linfócitos T CD8-Positivos / Doença Pulmonar Obstrutiva Crônica / Células Epiteliais / Proteínas ADAM / Proteínas de Membrana Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País como assunto: America do norte / Asia / Europa Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Brônquios / Macrófagos Alveolares / Linfócitos T CD8-Positivos / Doença Pulmonar Obstrutiva Crônica / Células Epiteliais / Proteínas ADAM / Proteínas de Membrana Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País como assunto: America do norte / Asia / Europa Idioma: En Ano de publicação: 2020 Tipo de documento: Article