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Therapeutic inhibition of FcγRIIb signaling targets leukemic stem cells in chronic myeloid leukemia.
Parting, Oliver; Langer, Samantha; Kuepper, Maja Kim; Wessling, Caroline; Li, Shaoguang; Braunschweig, Till; Chatain, Nicolas; Maié, Tiago; Costa, Ivan G; Crysandt, Martina; Huber, Michael; Brümmendorf, Tim H; Koschmieder, Steffen; Schemionek, Mirle.
Afiliação
  • Parting O; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, University Hospital RWTH Aachen, Aachen, Germany.
  • Langer S; Department of Transfusion Medicine, University Hospital Essen, Essen, Germany.
  • Kuepper MK; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, University Hospital RWTH Aachen, Aachen, Germany.
  • Wessling C; Department of Neurosurgery, Clemens Hospital, Muenster, Germany.
  • Li S; Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
  • Braunschweig T; Department of Pathology, University Hospital RWTH Aachen, Aachen, Germany.
  • Chatain N; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, University Hospital RWTH Aachen, Aachen, Germany.
  • Maié T; Institute for Computational Genomics, Joint Research Center for Computational Biomedicine, RWTH Aachen University, Aachen, Germany.
  • Costa IG; Institute for Computational Genomics, Joint Research Center for Computational Biomedicine, RWTH Aachen University, Aachen, Germany.
  • Crysandt M; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, University Hospital RWTH Aachen, Aachen, Germany.
  • Huber M; Institute of Biochemistry and Molecular Immunology, RWTH Aachen University, Aachen, Germany.
  • Brümmendorf TH; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, University Hospital RWTH Aachen, Aachen, Germany.
  • Koschmieder S; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, University Hospital RWTH Aachen, Aachen, Germany.
  • Schemionek M; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, University Hospital RWTH Aachen, Aachen, Germany. mschemionek@ukaachen.de.
Leukemia ; 34(10): 2635-2647, 2020 10.
Article em En | MEDLINE | ID: mdl-32684632
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Leucemia Mielogênica Crônica BCR-ABL Positiva / Transdução de Sinais / Proteínas de Fusão bcr-abl / Receptores de IgG / Inibidores de Proteínas Quinases / Tirosina Quinase da Agamaglobulinemia / Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Leucemia Mielogênica Crônica BCR-ABL Positiva / Transdução de Sinais / Proteínas de Fusão bcr-abl / Receptores de IgG / Inibidores de Proteínas Quinases / Tirosina Quinase da Agamaglobulinemia / Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article