Low Shear Stress Upregulates CX3CR1 Expression by Inducing VCAM-1 via the NF-&#954;B Pathway in Vascular Endothelial Cells.

Zhao, Yiwei; Ren, Peile; Li, Qiufang; Umar, Shafiu Adam; Yang, Tan; Dong, Yahui; Yu, Fengxu; Nie, Yongmei

Low Shear Stress Upregulates CX3CR1 Expression by Inducing VCAM-1 via the NF-κB Pathway in Vascular Endothelial Cells.

Zhao, Yiwei; Ren, Peile; Li, Qiufang; Umar, Shafiu Adam; Yang, Tan; Dong, Yahui; Yu, Fengxu; Nie, Yongmei.

Afiliação

Zhao Y; Department of Physiology, School of Medicine, Xinjiang Medical University, Urumqi, 830011, Xinjiang, PR China.
Ren P; Department of Physiology, School of Medicine, Xinjiang Medical University, Urumqi, 830011, Xinjiang, PR China.
Li Q; Department of Cardiovascular Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, PR China.
Umar SA; Department of Cardiovascular Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, PR China.
Yang T; Department of Cardiovascular Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, PR China.
Dong Y; Department of Cardiovascular Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, PR China.
Yu F; Department of Cardiovascular Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, PR China. yuluchuan@163.com.
Nie Y; Department of Cardiovascular Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, PR China. nieyongmei@126.com.

Cell Biochem Biophys ; 78(3): 383-389, 2020 Sep.

Article em En | MEDLINE | ID: mdl-32686027

Assuntos

Receptor 1 de Quimiocina CX3C/metabolismo; Células Endoteliais/metabolismo; Subunidade p50 de NF-kappa B/metabolismo; Resistência ao Cisalhamento; Molécula 1 de Adesão de Célula Vascular/biossíntese; Sobrevivência Celular; Células Cultivadas; Inativação Gênica; Células Endoteliais da Veia Umbilical Humana; Humanos; Inflamação; Microscopia de Fluorescência; Transdução de Sinais; Estresse Mecânico; Regulação para Cima

Palavras-chave

Atherosclerosis; CX3CR1; Human vascular endothelial cells; Low shear stress; NF-κB

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Molécula 1 de Adesão de Célula Vascular / Resistência ao Cisalhamento / Células Endoteliais / Subunidade p50 de NF-kappa B / Receptor 1 de Quimiocina CX3C Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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