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Design and synthesis of novel pyridazine N-aryl acetamides: In-vitro evaluation of α-glucosidase inhibition, docking, and kinetic studies.
Moghimi, Setareh; Toolabi, Mahsa; Salarinejad, Somayeh; Firoozpour, Loghman; Sadat Ebrahimi, Seyed Esmaeil; Safari, Fatemeh; Mojtabavi, Somayeh; Faramarzi, Mohammad Ali; Foroumadi, Alireza.
Afiliação
  • Moghimi S; Drug Design and Development Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran.
  • Toolabi M; Department of Medicinal Chemistry, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
  • Salarinejad S; Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
  • Firoozpour L; Drug Design and Development Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran.
  • Sadat Ebrahimi SE; Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
  • Safari F; Department of Biology, Faculty of Science, University of Guilan, Rasht, Iran.
  • Mojtabavi S; Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
  • Faramarzi MA; Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
  • Foroumadi A; Drug Design and Development Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran; Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: aforoumadi@yahoo.com.
Bioorg Chem ; 102: 104071, 2020 09.
Article em En | MEDLINE | ID: mdl-32688112
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Alfa-Glucosidases / Simulação de Acoplamento Molecular / Inibidores de Glicosídeo Hidrolases / Acetamidas Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Alfa-Glucosidases / Simulação de Acoplamento Molecular / Inibidores de Glicosídeo Hidrolases / Acetamidas Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article