Biodegradable hollow mesoporous organosilica nanotheranostics (HMON) for multi-mode imaging and mild photo-therapeutic-induced mitochondrial damage on gastric cancer.

Guo, Weihong; Chen, Zhian; Chen, Jiajia; Feng, Xiaoli; Yang, Yang; Huang, Huilin; Liang, Yanrui; Shen, Guodong; Liang, Yu; Peng, Chao; Li, Yanbing; Li, Guoxin; Huang, Wenhua; Zhao, Bingxia; Hu, Yanfeng

Guo, Weihong; Chen, Zhian; Chen, Jiajia; Feng, Xiaoli; Yang, Yang; Huang, Huilin; Liang, Yanrui; Shen, Guodong; Liang, Yu; Peng, Chao; Li, Yanbing; Li, Guoxin; Huang, Wenhua; Zhao, Bingxia; Hu, Yanfeng.

Afiliação

Guo W; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Chen Z; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Chen J; National Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510000, China.
Feng X; Guangdong Provincial Stomatology Hospital, Southern Medical University, Guangzhou, 510000, China.
Yang Y; National Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510000, China.
Huang H; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Liang Y; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Shen G; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Liang Y; Department of Medicine Ultrasonics, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Peng C; Guangdong Provincial Key Laboratory of Cancer Immunotherapy, Guangzhou Key Laboratory of Tumor Immunology Research, Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Li Y; Department of Medicine Ultrasonics, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Li G; Guangdong Provincial Key Laboratory of Cancer Immunotherapy, Guangzhou Key Laboratory of Tumor Immunology Research, Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Huang W; National Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510000, China.
Zhao B; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Hu Y; National Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510000, China. huangwenhua2009@139.com.

J Nanobiotechnology ; 18(1): 99, 2020 Jul 20.

Article em En | MEDLINE | ID: mdl-32690085

Assuntos

Mitocôndrias; Imagem Multimodal/métodos; Compostos de Organossilício; Fototerapia/métodos; Neoplasias Gástricas; Antineoplásicos/química; Antineoplásicos/farmacologia; Linhagem Celular Tumoral; Sobrevivência Celular/efeitos dos fármacos; Sulfato de Cobre; Humanos; Imageamento por Ressonância Magnética; Mitocôndrias/patologia; Mitocôndrias/efeitos da radiação; Compostos de Organossilício/química; Compostos de Organossilício/farmacologia; Neoplasias Gástricas/diagnóstico por imagem; Neoplasias Gástricas/patologia; Neoplasias Gástricas/terapia; Nanomedicina Teranóstica

Palavras-chave

Hollow mesoporous organosilica nanoparticles (HMON); Mitochondrial damage; Multi-modal imaging; Photo-dynamic therapy (PDT); Photo-thermal therapy (PTT)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fototerapia / Neoplasias Gástricas / Compostos de Organossilício / Imagem Multimodal / Mitocôndrias Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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