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Tectorigenin enhances PDX1 expression and protects pancreatic ß-cells by activating ERK and reducing ER stress.
Yao, Xinlei; Li, Kun; Liang, Chen; Zhou, Zilong; Wang, Jiao; Wang, Shuyue; Liu, Lei; Yu, Chun-Lei; Song, Zhen-Bo; Bao, Yong-Li; Zheng, Li-Hua; Sun, Ying; Wang, Guannan; Huang, Yanxin; Yi, Jingwen; Sun, Luguo; Li, Yuxin.
Afiliação
  • Yao X; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, China; Research Center of Agriculture and Medicine gene Engineering of Ministry of Education, Northeast Normal University, Changchun, China.
  • Li K; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, China.
  • Liang C; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, China.
  • Zhou Z; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, China.
  • Wang J; Research Center of Agriculture and Medicine gene Engineering of Ministry of Education, Northeast Normal University, Changchun, China.
  • Wang S; Research Center of Agriculture and Medicine gene Engineering of Ministry of Education, Northeast Normal University, Changchun, China.
  • Liu L; Research Center of Agriculture and Medicine gene Engineering of Ministry of Education, Northeast Normal University, Changchun, China.
  • Yu CL; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, China.
  • Song ZB; Research Center of Agriculture and Medicine gene Engineering of Ministry of Education, Northeast Normal University, Changchun, China.
  • Bao YL; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, China.
  • Zheng LH; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, China.
  • Sun Y; Research Center of Agriculture and Medicine gene Engineering of Ministry of Education, Northeast Normal University, Changchun, China.
  • Wang G; Research Center of Agriculture and Medicine gene Engineering of Ministry of Education, Northeast Normal University, Changchun, China.
  • Huang Y; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, China.
  • Yi J; Research Center of Agriculture and Medicine gene Engineering of Ministry of Education, Northeast Normal University, Changchun, China.
  • Sun L; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, China. Electronic address: sunlg388@nenu.edu.cn.
  • Li Y; Research Center of Agriculture and Medicine gene Engineering of Ministry of Education, Northeast Normal University, Changchun, China. Electronic address: liyx486@nenu.edu.cn.
J Biol Chem ; 295(37): 12975-12992, 2020 09 11.
Article em En | MEDLINE | ID: mdl-32690606

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transativadores / Regulação da Expressão Gênica / Regiões Promotoras Genéticas / Proteínas de Homeodomínio / Sistema de Sinalização das MAP Quinases / Células Secretoras de Insulina / Estresse do Retículo Endoplasmático / Isoflavonas Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transativadores / Regulação da Expressão Gênica / Regiões Promotoras Genéticas / Proteínas de Homeodomínio / Sistema de Sinalização das MAP Quinases / Células Secretoras de Insulina / Estresse do Retículo Endoplasmático / Isoflavonas Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article