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Glucocorticoid-induced tumour necrosis factor receptor family-related protein (GITR) drives atherosclerosis in mice and is associated with an unstable plaque phenotype and cerebrovascular events in humans.
Shami, Annelie; Atzler, Dorothee; Bosmans, Laura A; Winkels, Holger; Meiler, Svenja; Lacy, Michael; van Tiel, Claudia; Ta Megens, Remco; Nitz, Katrin; Baardman, Jeroen; Kusters, Pascal; Seijkens, Tom; Buerger, Christina; Janjic, Aleksandar; Riccardi, Carlo; Edsfeldt, Andreas; Monaco, Claudia; Daemen, Mat; de Winther, Menno P J; Nilsson, Jan; Weber, Christian; Gerdes, Norbert; Gonçalves, Isabel; Lutgens, Esther.
Afiliação
  • Shami A; Experimental Vascular Biology Division, Department of Medical Biochemistry, University of Amsterdam, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Atzler D; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians Universität, München, Germany.
  • Bosmans LA; Walther-Straub-Institute of Pharmacology and Toxicology, Ludwig-Maximilians Universität, München, Germany.
  • Winkels H; German Center for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany.
  • Meiler S; Experimental Vascular Biology Division, Department of Medical Biochemistry, University of Amsterdam, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Lacy M; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians Universität, München, Germany.
  • van Tiel C; Department of Inflammation Biology, La Jolla Institute for Immunology, La Jolla, CA, USA.
  • Ta Megens R; Experimental Vascular Biology Division, Department of Medical Biochemistry, University of Amsterdam, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Nitz K; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians Universität, München, Germany.
  • Baardman J; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians Universität, München, Germany.
  • Kusters P; German Center for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany.
  • Seijkens T; Experimental Vascular Biology Division, Department of Medical Biochemistry, University of Amsterdam, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Buerger C; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians Universität, München, Germany.
  • Janjic A; Cardiovascular Research Institute Maastricht (CARIM), Department of Biochemistry, Maastricht University, Maastricht, The Netherlands.
  • Riccardi C; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians Universität, München, Germany.
  • Edsfeldt A; Experimental Vascular Biology Division, Department of Medical Biochemistry, University of Amsterdam, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Monaco C; Experimental Vascular Biology Division, Department of Medical Biochemistry, University of Amsterdam, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Daemen M; Experimental Vascular Biology Division, Department of Medical Biochemistry, University of Amsterdam, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • de Winther MPJ; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians Universität, München, Germany.
  • Nilsson J; Anthropology & Human Genomics, Department of Biology II, Ludwig-Maximilians-Universität, München, Martinsried, Germany.
  • Weber C; Department of Medicine, Università degli Studi di Perugia, Perugia, Italy.
  • Gerdes N; Department of Clinical Sciences Malmö, Lund University, Clinical Research Center, Malmö, Sweden.
  • Gonçalves I; Department of Cardiology, Skåne University Hospital, Lund University, Sweden.
  • Lutgens E; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK.
Eur Heart J ; 41(31): 2938-2948, 2020 08 14.
Article em En | MEDLINE | ID: mdl-32728688
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aterosclerose / Proteína Relacionada a TNFR Induzida por Glucocorticoide / Placa Aterosclerótica Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aterosclerose / Proteína Relacionada a TNFR Induzida por Glucocorticoide / Placa Aterosclerótica Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article