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A Proof of Concept for Biomarker-Guided Targeted Therapy against Ovarian Cancer Based on Patient-Derived Tumor Xenografts.
Palmer, Adam C; Plana, Deborah; Gao, Hui; Korn, Joshua M; Yang, Guizhi; Green, John; Zhang, Xiamei; Velazquez, Roberto; McLaughlin, Margaret E; Ruddy, David A; Kowal, Colleen; Muszynski, Julie; Bullock, Caroline; Rivera, Stacy; Rakiec, Daniel P; Elliott, GiNell; Fordjour, Paul; Meyer, Ronald; Loo, Alice; Kurth, Esther; Engelman, Jeffrey A; Bitter, Hans; Sellers, William R; Williams, Juliet A; Sorger, Peter K.
Afiliação
  • Palmer AC; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, Massachusetts.
  • Plana D; Department of Pharmacology, Computational Medicine Program, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
  • Gao H; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, Massachusetts.
  • Korn JM; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts.
  • Yang G; Harvard-MIT Division of Health Sciences and Technology, Harvard Medical School and MIT, Cambridge, Massachusetts.
  • Green J; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Zhang X; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Velazquez R; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • McLaughlin ME; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Ruddy DA; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Kowal C; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Muszynski J; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Bullock C; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Rivera S; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Rakiec DP; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Elliott G; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Fordjour P; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Meyer R; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Loo A; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Kurth E; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Engelman JA; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Bitter H; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Sellers WR; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Williams JA; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
  • Sorger PK; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts.
Cancer Res ; 80(19): 4278-4287, 2020 10 01.
Article em En | MEDLINE | ID: mdl-32747364
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Protocolos de Quimioterapia Combinada Antineoplásica / Biomarcadores Tumorais / Ensaios Antitumorais Modelo de Xenoenxerto Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Protocolos de Quimioterapia Combinada Antineoplásica / Biomarcadores Tumorais / Ensaios Antitumorais Modelo de Xenoenxerto Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article