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An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease.
Brubaker, Douglas K; Kumar, Manu P; Chiswick, Evan L; Gregg, Cecil; Starchenko, Alina; Vega, Paige N; Southard-Smith, Austin N; Simmons, Alan J; Scoville, Elizabeth A; Coburn, Lori A; Wilson, Keith T; Lau, Ken S; Lauffenburger, Douglas A.
Afiliação
  • Brubaker DK; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Kumar MP; Department of Biomedical Engineering, Purdue University, West Lafayette, IN 47906, USA.
  • Chiswick EL; Regenstrief Center for Healthcare Engineering, Purdue University, West Lafayette, IN 47906, USA.
  • Gregg C; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Starchenko A; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Vega PN; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Southard-Smith AN; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Simmons AJ; Epithelial Biology Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Scoville EA; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232, USA.
  • Coburn LA; Epithelial Biology Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Wilson KT; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232, USA.
  • Lau KS; Epithelial Biology Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Lauffenburger DA; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232, USA.
Sci Signal ; 13(643)2020 08 04.
Article em En | MEDLINE | ID: mdl-32753478
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência a Medicamentos / Doenças Inflamatórias Intestinais / Transdução de Sinais / Integrinas / Integrina alfa1 / Infliximab Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência a Medicamentos / Doenças Inflamatórias Intestinais / Transdução de Sinais / Integrinas / Integrina alfa1 / Infliximab Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article