Spatial heterogeneity of radiolabeled choline positron emission tomography in tumors of patients with non-small cell lung cancer: first-in-patient evaluation of [18F]fluoromethyl-(1,2-2H4)-choline.

Dubash, Suraiya; Inglese, Marianna; Mauri, Francesco; Kozlowski, Kasia; Trivedi, Pritesh; Arshad, Mubarik; Challapalli, Amarnath; Barwick, Tara; Al-Nahhas, Adil; Stanbridge, Rex; Lewanski, Conrad; Berry, Matthew; Bowen, Frances; Aboagye, Eric O

Spatial heterogeneity of radiolabeled choline positron emission tomography in tumors of patients with non-small cell lung cancer: first-in-patient evaluation of [¹⁸F]fluoromethyl-(1,2-²H₄)-choline.

Dubash, Suraiya; Inglese, Marianna; Mauri, Francesco; Kozlowski, Kasia; Trivedi, Pritesh; Arshad, Mubarik; Challapalli, Amarnath; Barwick, Tara; Al-Nahhas, Adil; Stanbridge, Rex; Lewanski, Conrad; Berry, Matthew; Bowen, Frances; Aboagye, Eric O.

Afiliação

Dubash S; Department of Surgery and Cancer, Imperial College London, United Kingdom.
Inglese M; Department of Surgery and Cancer, Imperial College London, United Kingdom.
Mauri F; Department of Surgery and Cancer, Imperial College London, United Kingdom.
Kozlowski K; Department of Surgery and Cancer, Imperial College London, United Kingdom.
Trivedi P; Department of Surgery and Cancer, Imperial College London, United Kingdom.
Arshad M; Department of Surgery and Cancer, Imperial College London, United Kingdom.
Challapalli A; Department of Radiology/Nuclear Medicine, Imperial College Healthcare NHS Trust, London, United Kingdom.
Barwick T; Department of Surgery and Cancer, Imperial College London, United Kingdom.
Al-Nahhas A; Department of Surgery and Cancer, Imperial College London, United Kingdom.
Stanbridge R; Department of Radiology/Nuclear Medicine, Imperial College Healthcare NHS Trust, London, United Kingdom.
Lewanski C; Department of Radiology/Nuclear Medicine, Imperial College Healthcare NHS Trust, London, United Kingdom.
Berry M; Department of Surgery and Cancer, Imperial College Healthcare NHS Trust, London, United Kingdom.
Bowen F; Department of Surgery and Cancer, Imperial College Healthcare NHS Trust, London, United Kingdom.
Aboagye EO; Department of Medicine and Integrated Care, Imperial College Healthcare NHS Trust, London, United Kingdom.

Theranostics ; 10(19): 8677-8690, 2020.

Article em En | MEDLINE | ID: mdl-32754271

Assuntos

Carcinoma Pulmonar de Células não Pequenas/diagnóstico por imagem; Colina Quinase/metabolismo; Colina/análogos & derivados; Deutério/química; Neoplasias Pulmonares/diagnóstico por imagem; Administração Intravenosa; Adulto; Idoso; Idoso de 80 Anos ou mais; Carcinoma Pulmonar de Células não Pequenas/metabolismo; Colina/administração & dosagem; Colina/química; Colina/farmacologia; Estudos de Viabilidade; Feminino; Humanos; Neoplasias Pulmonares/metabolismo; Metástase Linfática; Masculino; Pessoa de Meia-Idade; Modelos Teóricos; Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada; Estudos Prospectivos; Sensibilidade e Especificidade

Palavras-chave

2-2H4)-choline; Positron Emission Tomography; [18F] Fluoromethyl-(1; choline kinase alpha; heterogeneity choline metabolism; lung cancer.

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colina / Colina Quinase / Carcinoma Pulmonar de Células não Pequenas / Deutério / Neoplasias Pulmonares Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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