POT1-TPP1 telomere length regulation and disease.

Aramburu, Tomas; Plucinsky, Sarah; Skordalakes, Emmanuel.

Afiliação

Aramburu T; The Wistar Institute, 3601 Spruce St, Philadelphia, PA 19104, USA.
Plucinsky S; The Wistar Institute, 3601 Spruce St, Philadelphia, PA 19104, USA.
Skordalakes E; The Wistar Institute, 3601 Spruce St, Philadelphia, PA 19104, USA.

Comput Struct Biotechnol J ; 18: 1939-1946, 2020.

Article em En | MEDLINE | ID: mdl-32774788

Palavras-chave

ATM, Ataxia Telangiectasia Mutated protein; ATR, Ataxia Telangiectasia and Rad3-related Protein; CST, CTC1, Stn1 and Ten1; CTC1, Conserved Telomere Capping Protein 1; POT1; POT1, Protection of telomere 1; RAP1, Repressor/Activator Protein 1; RPA, Replication Protein A; SMCHD1, Structural Maintenance Of Chromosomes Flexible Hinge Domain Containing 1; Shelterin; Stn1, Suppressor of Cdc Thirteen; TERC, Telomerase RNA; TERT, Telomerase Reverse Transcriptase; TIN2, TRF1- and TRF2-Interacting Nuclear Protein 2; TPP1; TPP1 also known as ACD, Adrenocortical Dysplasia Protein Homolog; TRF1, Telomere Repeat binding Factor 1; TRF2, Telomere Repeat binding Factor 2; TSPYL5, Testis-specific Y-encoded-like protein 5; Telomerase; Telomeres; Ten1, Telomere Length Regulation Protein; USP7, ubiquitin-specific-processing protease 7

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article