UV-Induced 1,3,4-Oxadiazole Formation from 5-Substituted Tetrazoles and Carboxylic Acids in Flow.
Chemistry
; 26(65): 14866-14870, 2020 Nov 20.
Article
em En
| MEDLINE
| ID: mdl-32786060
ABSTRACT
A range of 1,3,4-oxadiazoles have been synthesized using a UV-B activated flow approach starting from carboxylic acids and 5-substituted tetrazoles. The application of UV light represents an attractive alternative to the traditional thermolytic approach and has demonstrated comparable efficiency and versatility, with a diverse substrate scope, including the incorporation of highly substituted amino acids.
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MEDLINE
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En
Ano de publicação:
2020
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Article