HIV-cell membrane fusion intermediates are restricted by Serincs as revealed by cryo-electron and TIRF microscopy.

Ward, Amanda E; Kiessling, Volker; Pornillos, Owen; White, Judith M; Ganser-Pornillos, Barbie K; Tamm, Lukas K

Ward, Amanda E; Kiessling, Volker; Pornillos, Owen; White, Judith M; Ganser-Pornillos, Barbie K; Tamm, Lukas K.

Afiliação

Ward AE; Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Kiessling V; Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Pornillos O; Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
White JM; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Ganser-Pornillos BK; Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, Virginia, USA. Electronic address: bkg7q@virginia.edu.
Tamm LK; Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, Virginia, USA; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA. Electronic address: lkt2e@virginia.edu.

J Biol Chem ; 295(45): 15183-15195, 2020 11 06.

Article em En | MEDLINE | ID: mdl-32788212

Assuntos

Membrana Celular/metabolismo; Microscopia Crioeletrônica; HIV-1/metabolismo; Glicoproteínas de Membrana/metabolismo; Proteínas de Membrana/metabolismo; Linhagem Celular; Células HEK293; Células HeLa; Interações Hospedeiro-Patógeno; Humanos; Fusão de Membrana; Microscopia de Fluorescência; Produtos do Gene env do Vírus da Imunodeficiência Humana/metabolismo

Palavras-chave

HIV; cryo-electron microscopy; host-pathogen interaction; human immunodeficiency virus (HIV); membrane fusion; single-particle tracking; virus entry

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Membrana Celular / HIV-1 / Microscopia Crioeletrônica / Proteínas de Membrana Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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