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The African natural product knipholone anthrone and its analogue anthralin (dithranol) enhance HIV-1 latency reversal.
Richard, Khumoekae; Schonhofer, Cole; Giron, Leila B; Rivera-Ortiz, Jocelyn; Read, Silven; Kannan, Toshitha; Kinloch, Natalie N; Shahid, Aniqa; Feilcke, Ruth; Wappler, Simone; Imming, Peter; Harris, Marianne; Brumme, Zabrina L; Brockman, Mark A; Mounzer, Karam; Kossenkov, Andrew V; Abdel-Mohsen, Mohamed; Andrae-Marobela, Kerstin; Montaner, Luis J; Tietjen, Ian.
Afiliação
  • Richard K; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
  • Schonhofer C; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
  • Giron LB; Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Rivera-Ortiz J; Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Read S; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
  • Kannan T; Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Kinloch NN; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
  • Shahid A; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada.
  • Feilcke R; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
  • Wappler S; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada.
  • Imming P; Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany.
  • Harris M; Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany.
  • Brumme ZL; Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany.
  • Brockman MA; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada.
  • Mounzer K; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
  • Kossenkov AV; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada.
  • Abdel-Mohsen M; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
  • Andrae-Marobela K; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada.
  • Montaner LJ; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada.
  • Tietjen I; Jonathan Lax Immune Disorders Treatment Center, Philadelphia Field Initiating Group for HIV-1 Trials, Philadelphia, Pennsylvania, USA.
J Biol Chem ; 295(41): 14084-14099, 2020 10 09.
Article em En | MEDLINE | ID: mdl-32788215
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / Antralina / HIV-1 / Latência Viral / Antracenos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / Antralina / HIV-1 / Latência Viral / Antracenos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article