Efficient whole brain transduction by systemic infusion of minimally purified AAV-PHP.eB.

Konno, Ayumu; Hirai, Hirokazu

Konno, Ayumu; Hirai, Hirokazu.

Afiliação

Konno A; Department of Neurophysiology and Neural Repair, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan; Viral Vector Core, Gunma University Initiative for Advanced Research (GIAR), 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan.
Hirai H; Department of Neurophysiology and Neural Repair, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan; Viral Vector Core, Gunma University Initiative for Advanced Research (GIAR), 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan. Electronic address: hirai@gunma-u.ac.jp.

J Neurosci Methods ; 346: 108914, 2020 12 01.

Article em En | MEDLINE | ID: mdl-32810474

Assuntos

Dependovirus; Vetores Genéticos; Animais; Encéfalo; Dependovirus/genética; Terapia Genética; Camundongos; Transdução Genética

Palavras-chave

AAV; AAV-PHP.eB; Adeno-associated virus; Blood brain barrier; Gene transduction; Ultracentrifuge

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dependovirus / Vetores Genéticos Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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