A new cyclopeptide alkaloid from Clematis Florida.
Nat Prod Res
; 36(7): 1693-1699, 2022 Apr.
Article
em En
| MEDLINE
| ID: mdl-32811200
ABSTRACT
One new 14-membered ring cyclopeptide alkaloid, plenane A (1), along with six known compounds (2-7), was isolated from the roots of Clematis florida. Their structures were elucidated by means of NMR spectroscopic analysis and mass spectrometry. In addition, their anti- inflammatory effects on lipopolysaccharide-induced RAW264.7 macrophages were evaluated in vitro. The compounds 1, 2 and 6 exhibited potent indirect inhibitory effects, with IC50 values of 40.92, 22.88 and 6.32 µM, respectively.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Clematis
/
Alcaloides
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article