A high throughput screen for TMPRSS2 expression identifies FDA-approved and clinically advanced compounds that can limit SARS-CoV-2 entry.

Chen, Yanwen; Lear, Travis B; Evankovich, John W; Larsen, Mads B; Lin, Bo; Alfaras, Irene; Kennerdell, Jason R; Salminen, Laura; Camarco, Daniel P; Lockwood, Karina C; Liu, Jie; Myerburg, Michael M; McDyer, John F; Liu, Yuan; Finkel, Toren; Chen, Bill B

Chen, Yanwen; Lear, Travis B; Evankovich, John W; Larsen, Mads B; Lin, Bo; Alfaras, Irene; Kennerdell, Jason R; Salminen, Laura; Camarco, Daniel P; Lockwood, Karina C; Liu, Jie; Myerburg, Michael M; McDyer, John F; Liu, Yuan; Finkel, Toren; Chen, Bill B.

Afiliação

Chen Y; Aging Institute, University of Pittsburgh/UPMC, Pittsburgh, PA 15219, USA.
Lear TB; Department of Gastroenterology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
Evankovich JW; Aging Institute, University of Pittsburgh/UPMC, Pittsburgh, PA 15219, USA.
Larsen MB; Department of Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Lin B; Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Alfaras I; Aging Institute, University of Pittsburgh/UPMC, Pittsburgh, PA 15219, USA.
Kennerdell JR; Department of Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Salminen L; Aging Institute, University of Pittsburgh/UPMC, Pittsburgh, PA 15219, USA.
Camarco DP; Aging Institute, University of Pittsburgh/UPMC, Pittsburgh, PA 15219, USA.
Lockwood KC; Aging Institute, University of Pittsburgh/UPMC, Pittsburgh, PA 15219, USA.
Liu J; Aging Institute, University of Pittsburgh/UPMC, Pittsburgh, PA 15219, USA.
Myerburg MM; Aging Institute, University of Pittsburgh/UPMC, Pittsburgh, PA 15219, USA.
McDyer JF; Aging Institute, University of Pittsburgh/UPMC, Pittsburgh, PA 15219, USA.
Liu Y; Aging Institute, University of Pittsburgh/UPMC, Pittsburgh, PA 15219, USA.
Finkel T; Aging Institute, University of Pittsburgh/UPMC, Pittsburgh, PA 15219, USA.
Chen BB; Department of Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, PA 15213, USA.

Res Sq ; 2020 Aug 14.

Article em En | MEDLINE | ID: mdl-32818215

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article