Circ_0010220-mediated miR-503-5p/CDCA4 axis contributes to osteosarcoma progression tumorigenesis.

Li, Jianping; Zhang, Feng; Li, Haohuan; Peng, Fei; Wang, Zhe; Peng, Hao; He, Jingxuan; Li, Ying; He, Lu; Wei, Liqing

Li, Jianping; Zhang, Feng; Li, Haohuan; Peng, Fei; Wang, Zhe; Peng, Hao; He, Jingxuan; Li, Ying; He, Lu; Wei, Liqing.

Afiliação

Li J; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China. Electronic address: ljpstar0220@163.com.
Zhang F; Department of Anesthesiology, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei, PR China.
Li H; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China.
Peng F; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China.
Wang Z; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China.
Peng H; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China.
He J; Department of Orthopedics, General Hospital of the Yangtze River Shipping, Wuhan 430010, Hubei, PR China.
Li Y; Physical Examination Center, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China.
He L; Physical Examination Center, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China.
Wei L; School of Health Sciences, Wuhan University, Wuhan 430014, Hubei, PR China.

Gene ; 763: 145068, 2020 Dec 30.

Article em En | MEDLINE | ID: mdl-32827680

Assuntos

Neoplasias Ósseas/genética; Proteínas de Ciclo Celular/genética; MicroRNAs/genética; Osteossarcoma/genética; RNA Circular/genética; Animais; Apoptose; Neoplasias Ósseas/metabolismo; Neoplasias Ósseas/patologia; Carcinogênese/genética; Carcinogênese/metabolismo; Proteínas de Ciclo Celular/metabolismo; Linhagem Celular Tumoral; Proliferação de Células; Pontos de Checagem da Fase G1 do Ciclo Celular; Regulação Neoplásica da Expressão Gênica; Humanos; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; MicroRNAs/metabolismo; Osteossarcoma/metabolismo; Osteossarcoma/patologia; RNA Circular/metabolismo

Palavras-chave

CDCA4; Circ_0010220; Osteosarcoma; miR-503-5p

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Osteossarcoma / Proteínas de Ciclo Celular / MicroRNAs / RNA Circular Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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