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Sunitinib inhibits RNase L by destabilizing its active dimer conformation.
Tang, Jinle; Wang, Yingjie; Zhou, Huan; Ye, Yuxin; Talukdar, Manisha; Fu, Ziyang; Liu, Zhihong; Li, Jihui; Neculai, Dante; Gao, Jiali; Huang, Hao.
Afiliação
  • Tang J; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
  • Wang Y; Shenzhen Bay Laboratory, Shenzhen, China.
  • Zhou H; Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shang Hai, China.
  • Ye Y; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
  • Talukdar M; Department of Molecular Genetics and Department of Biochemistry, University of Toronto, Toronto, Canada.
  • Fu Z; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada.
  • Liu Z; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
  • Li J; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
  • Neculai D; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
  • Gao J; Department of Cell Biology, Zhejiang University, School of Basic Medical Sciences, Hangzhou, China.
  • Huang H; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
Biochem J ; 477(17): 3387-3399, 2020 09 18.
Article em En | MEDLINE | ID: mdl-32830849
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Endorribonucleases / Multimerização Proteica / Sunitinibe Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Endorribonucleases / Multimerização Proteica / Sunitinibe Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article