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Thoracic radiotherapy plus Durvalumab in elderly and/or frail NSCLC stage III patients unfit for chemotherapy - employing optimized (hypofractionated) radiotherapy to foster durvalumab efficacy: study protocol of the TRADE-hypo trial.
Bozorgmehr, Farastuk; Chung, Inn; Christopoulos, Petros; Krisam, Johannes; Schneider, Marc A; Brückner, Lena; Mueller, Daniel Wilhelm; Thomas, Michael; Rieken, Stefan.
Afiliação
  • Bozorgmehr F; Department of Thoracic Oncology, Thoraxklinik at University Hospital of Heidelberg, Röntgenstraße 1, 69126, Heidelberg, Germany. Farastuk.Bozorgmehr@med.uni-heidelberg.de.
  • Chung I; Translational Lung Research Center Heidelberg TLRCH, Member of the German Center for Lung Research DZL, Im Neuenheimer Feld 156, 69120, Heidelberg, Germany. Farastuk.Bozorgmehr@med.uni-heidelberg.de.
  • Christopoulos P; Department of Thoracic Oncology, Thoraxklinik at University Hospital of Heidelberg, Röntgenstraße 1, 69126, Heidelberg, Germany.
  • Krisam J; Translational Lung Research Center Heidelberg TLRCH, Member of the German Center for Lung Research DZL, Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
  • Schneider MA; Department of Thoracic Oncology, Thoraxklinik at University Hospital of Heidelberg, Röntgenstraße 1, 69126, Heidelberg, Germany.
  • Brückner L; Translational Lung Research Center Heidelberg TLRCH, Member of the German Center for Lung Research DZL, Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
  • Mueller DW; Institute of Medical Biometry and Informatics, University Hospital of Heidelberg, Im Neuenheimer Feld 130.3, 69120, Heidelberg, Germany.
  • Thomas M; Translational Lung Research Center Heidelberg TLRCH, Member of the German Center for Lung Research DZL, Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
  • Rieken S; Thoraxklinik at University Hospital of Heidelberg, Translational Research Unit (STF), Röntgenstraße 1, 69126, Heidelberg, Germany.
BMC Cancer ; 20(1): 806, 2020 Aug 26.
Article em En | MEDLINE | ID: mdl-32842974
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Texto completo: 1 Eixos temáticos: Pesquisa_clinica Base de dados: MEDLINE Assunto principal: Pneumonite por Radiação / Carcinoma Pulmonar de Células não Pequenas / Quimiorradioterapia / Hipofracionamento da Dose de Radiação / Inibidores de Checkpoint Imunológico / Neoplasias Pulmonares Tipo de estudo: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Eixos temáticos: Pesquisa_clinica Base de dados: MEDLINE Assunto principal: Pneumonite por Radiação / Carcinoma Pulmonar de Células não Pequenas / Quimiorradioterapia / Hipofracionamento da Dose de Radiação / Inibidores de Checkpoint Imunológico / Neoplasias Pulmonares Tipo de estudo: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article