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Therapeutic vulnerabilities in the DNA damage response for the treatment of ATRX mutant neuroblastoma.
George, Sally L; Lorenzi, Federica; King, David; Hartlieb, Sabine; Campbell, James; Pemberton, Helen; Toprak, Umut H; Barker, Karen; Tall, Jennifer; da Costa, Barbara Martins; van den Boogaard, Marlinde L; Dolman, M Emmy M; Molenaar, Jan J; Bryant, Helen E; Westermann, Frank; Lord, Christopher J; Chesler, Louis.
Afiliação
  • George SL; Paediatric Tumour Biology, Division of Clinical Studies, The Institute of Cancer Research, Sutton, Surrey SM2 5NG, United Kingdom; Children and Young People's Unit, Royal Marsden NHS Foundation Trust, Sutton, Surrey SM2 5PT United Kingdom. Electronic address: Sally.George@icr.ac.uk.
  • Lorenzi F; Paediatric Tumour Biology, Division of Clinical Studies, The Institute of Cancer Research, Sutton, Surrey SM2 5NG, United Kingdom.
  • King D; Academic Unit of Molecular Oncology, Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Oncology and Metabolism, University of Sheffield, Beech Hill Road, Sheffield S10 2RX, United Kingdom.
  • Hartlieb S; Neuroblastoma Genomics, Hopp Children`s Cancer Center Heidelberg (KiTZ) & German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Campbell J; Bioinformatics Core Facility, The Institute of Cancer Research, London, United Kingdom.
  • Pemberton H; CRUK Gene Function Laboratory and Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research London, SW3 6JB, United Kingdom.
  • Toprak UH; Neuroblastoma Genomics, Hopp Children`s Cancer Center Heidelberg (KiTZ) & German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Barker K; Paediatric Tumour Biology, Division of Clinical Studies, The Institute of Cancer Research, Sutton, Surrey SM2 5NG, United Kingdom.
  • Tall J; Paediatric Tumour Biology, Division of Clinical Studies, The Institute of Cancer Research, Sutton, Surrey SM2 5NG, United Kingdom.
  • da Costa BM; Paediatric Tumour Biology, Division of Clinical Studies, The Institute of Cancer Research, Sutton, Surrey SM2 5NG, United Kingdom.
  • van den Boogaard ML; Princess Maxima Center for Pediatric Cancer, Utrecht, The Netherlands.
  • Dolman MEM; Princess Maxima Center for Pediatric Cancer, Utrecht, The Netherlands.
  • Molenaar JJ; Princess Maxima Center for Pediatric Cancer, Utrecht, The Netherlands.
  • Bryant HE; Academic Unit of Molecular Oncology, Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Oncology and Metabolism, University of Sheffield, Beech Hill Road, Sheffield S10 2RX, United Kingdom.
  • Westermann F; Neuroblastoma Genomics, Hopp Children`s Cancer Center Heidelberg (KiTZ) & German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Lord CJ; CRUK Gene Function Laboratory and Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research London, SW3 6JB, United Kingdom.
  • Chesler L; Paediatric Tumour Biology, Division of Clinical Studies, The Institute of Cancer Research, Sutton, Surrey SM2 5NG, United Kingdom; Children and Young People's Unit, Royal Marsden NHS Foundation Trust, Sutton, Surrey SM2 5PT United Kingdom.
EBioMedicine ; 59: 102971, 2020 Sep.
Article em En | MEDLINE | ID: mdl-32846370
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / Reparo do DNA / Proteína Nuclear Ligada ao X / Neuroblastoma / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / Reparo do DNA / Proteína Nuclear Ligada ao X / Neuroblastoma / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article