SARS-CoV-2 and the safety margins of cell-based biological medicinal products.
Biologicals
; 68: 122-124, 2020 Nov.
Article
em En
| MEDLINE
| ID: mdl-32891497
ABSTRACT
With the pandemic emergence of SARS-CoV-2, the exposure of cell substrates used for manufacturing of medicines has become a possibility. Cell lines used in biomanufacturing were thus evaluated for their SARS-CoV-2 susceptibility, and the detection of SARS-CoV-2 in culture supernatants by routine adventitious virus testing of fermenter harvest tested.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pneumonia Viral
/
Replicação Viral
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Infecções por Coronavirus
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Betacoronavirus
Limite:
Animals
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Humans
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article