Combination of carbon-ion beam and dual tyrosine kinase inhibitor, lapatinib, effectively destroys HER2 positive breast cancer stem-like cells.

Sai, Sei; Kim, Eun Ho; Vares, Guillaume; Suzuki, Masao; Yu, Dong; Horimoto, Yoshiya; Hayashi, Mitsuhiro.

Afiliação

Sai S; Department of Basic Medical Sciences for Radiation Damages, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology Chiba, Japan.
Kim EH; Department of Biochemistry, School of Medicine, Daegu Catholic University Nam-gu, Daegu 42472, South Korea.
Vares G; Okinawa Institute of Science and Technology (OIST), Advanced Medical Instrumentation Unit Tancha 1919-1, Onna-son, Okinawa 904-0495, Japan.
Suzuki M; Department of Basic Medical Sciences for Radiation Damages, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology Chiba, Japan.
Yu D; School of Radiological Medicine and Protection, Medical College of Soochow University Suzhou 215006, China.
Horimoto Y; Department of Breast Oncology, Juntendo University School of Medicine 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Hayashi M; Breast Center, Dokkyo Medical University Hospital 880 Kita-Kobayashi, Mibu-machi, Shimotsuga-gun, Tochigi 321-0293, Japan.

Am J Cancer Res ; 10(8): 2371-2386, 2020.

Article em En | MEDLINE | ID: mdl-32905515