Impact of Ruptured Aneurysm Circulation on Mortality: A Nationwide Inpatient Sample Analysis.
J Stroke Cerebrovasc Dis
; 29(10): 105124, 2020 Oct.
Article
em En
| MEDLINE
| ID: mdl-32912535
ABSTRACT
OBJECTIVE:
This study investigates the effect of aneurysm circulation on mortality and patient outcomes after aneurysmal subarachnoid hemorrhage (SAH) within the United States.METHODS:
A retrospective cohort study was conducted using the Nationwide Inpatient Sample (NIS), a part of the Healthcare Cost and Utilization Project (HCUP), with ICD-10 codes for non-traumatic SAH between 2015-2016. Aneurysms were stratified as either anterior or posterior circulation. Multivariate logistic regression was used to find the impact of selected variables on the odds of mortality.RESULTS:
The NIS reported 1,892 cases of non-traumatic SAH within the study period that were predominantly anterior circulation (82.6%), female (68.6%), white (57.7%), with mean age of 59.07 years, and in-hospital mortality of 21.4%. Anterior circulation aneurysms were associated with lower severity of initial illness (pâ¯=â¯0.014) but higher likelihood of vasospasm (pâ¯=â¯0.0006) than those of the posterior circulation. In a multivariate logistic regression analysis, mortality was associated with posterior circulation aneurysms (OR 1.42; CI 95% 1.005-20.10, pâ¯=â¯0.047), increasing age (OR 1.035; 95% CI 1.022-1.049; p < 0.0001), and shorter hospital stays (OR 0.7838; 95% CI 0.758-0.811; p < 0.0001). Smoking history (OR 0.825; 95% CI 0.573-1.187, p > 0.05) and vasospasm (OR 1.005; 95% CI 0.648-1.558; p > 0.05) were not significantly associated with higher odds of mortality.CONCLUSIONS:
Mortality following aneurysmal SAH is associated with posterior circulation aneurysms, and increasing age, but not smoking history or vasospasm. These findings may be useful for prognostication and counseling patients and families.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Hemorragia Subaracnóidea
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Aneurisma Intracraniano
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Circulação Cerebrovascular
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Mortalidade Hospitalar
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Aneurisma Roto
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article