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Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment.
Liu, Xu; Wang, Yashuo; Gutierrez, Jennifer S; Damsker, Jesse M; Nagaraju, Kanneboyina; Hoffman, Eric P; Ortlund, Eric A.
Afiliação
  • Liu X; Department of Biochemistry, Emory University, Atlanta, GA 30322.
  • Wang Y; Department of Biochemistry, Emory University, Atlanta, GA 30322.
  • Gutierrez JS; Department of Biochemistry, Emory University, Atlanta, GA 30322.
  • Damsker JM; ReveraGen Biopharma, LLC, Rockville, MD 20850.
  • Nagaraju K; ReveraGen Biopharma, LLC, Rockville, MD 20850.
  • Hoffman EP; Department of Pharmaceutical Sciences, Binghamton University, State University of New York, Binghamton, NY 13902.
  • Ortlund EA; ReveraGen Biopharma, LLC, Rockville, MD 20850.
Proc Natl Acad Sci U S A ; 117(39): 24285-24293, 2020 09 29.
Article em En | MEDLINE | ID: mdl-32917814

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pregnadienodiois / Distrofia Muscular de Duchenne Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pregnadienodiois / Distrofia Muscular de Duchenne Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article