Transcatheter Treatment of Functional Mitral Regurgitation in Patients with Heart Failure: The COAPT Trial.
Interv Cardiol Clin
; 9(4): 451-459, 2020 10.
Article
em En
| MEDLINE
| ID: mdl-32921369
ABSTRACT
Secondary (functional) mitral regurgitation is strongly associated with recurrent heart failure (HF) hospitalizations, poor quality of life, and high rates of mortality. The COAPT trial demonstrated that transcatheter edge-to-edge mitral leaflet repair with the MitraClip device led to a decrease in the severity of secondary mitral regurgitation, a significantly lower rate of hospitalization for heart failure, lower mortality, and better quality of life and functional capacity within 24 months of follow-up compared with medical therapy alone. In this article, the authors review the COAPT trial rationale, design, results, and their clinical implications.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Cateterismo Cardíaco
/
Implante de Prótese de Valva Cardíaca
/
Insuficiência Cardíaca
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Valva Mitral
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Insuficiência da Valva Mitral
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article