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Excessive deubiquitination of NLRP3-R779C variant contributes to very-early-onset inflammatory bowel disease development.
Zhou, Lingli; Liu, Tao; Huang, Bing; Luo, Man; Chen, Zhanghua; Zhao, Zhiyao; Wang, Jun; Leung, Daniel; Yang, Xingtian; Chan, Koon Wing; Liu, Yukun; Xiong, Liya; Chen, Peiyu; Wang, Hongli; Ye, Liping; Liang, Hanquan; Masters, Seth L; Lew, Andrew M; Gong, Sitang; Bai, Fan; Yang, Jing; Pui-Wah Lee, Pamela; Yang, Wanling; Zhang, Yan; Lau, Yu-Lung; Geng, Lanlan; Zhang, Yuxia; Cui, Jun.
Afiliação
  • Zhou L; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
  • Liu T; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
  • Huang B; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China; Guangdong Provincial Key Laboratory of Gastroenterology, Departm
  • Luo M; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
  • Chen Z; Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, Peking University, Beijing, China.
  • Zhao Z; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
  • Wang J; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
  • Leung D; the Department of Pediatrics & Adolescent Medicine, The University of Hong Kong, Hong Kong, China.
  • Yang X; the Department of Pediatrics & Adolescent Medicine, The University of Hong Kong, Hong Kong, China.
  • Chan KW; the Department of Pediatrics & Adolescent Medicine, The University of Hong Kong, Hong Kong, China.
  • Liu Y; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
  • Xiong L; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
  • Chen P; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
  • Wang H; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
  • Ye L; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
  • Liang H; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
  • Masters SL; Walter and Eliza Hall Institute of Medical Research and Departments of Medical Biology and Microbiology & Immunology, University of Melbourne, Parkville, Melbourne, Australia.
  • Lew AM; Walter and Eliza Hall Institute of Medical Research and Departments of Medical Biology and Microbiology & Immunology, University of Melbourne, Parkville, Melbourne, Australia.
  • Gong S; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
  • Bai F; Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, Peking University, Beijing, China.
  • Yang J; the Department of Pediatrics & Adolescent Medicine, The University of Hong Kong, Hong Kong, China.
  • Pui-Wah Lee P; the Department of Pediatrics & Adolescent Medicine, The University of Hong Kong, Hong Kong, China.
  • Yang W; the Department of Pediatrics & Adolescent Medicine, The University of Hong Kong, Hong Kong, China.
  • Zhang Y; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
  • Lau YL; the Department of Pediatrics & Adolescent Medicine, The University of Hong Kong, Hong Kong, China. Electronic address: lauylung@hku.hk.
  • Geng L; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China. Electronic address: genglan_2001@hotmail.com.
  • Zhang Y; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China. Electronic address: yuxia.zhang@gwcmc.org.
  • Cui J; MOE Key Laboratory of Gene Function and Regulation, Department of Gastroenterology and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou, China. Electronic address: cuij5@mail.sysu.edu.cn.
J Allergy Clin Immunol ; 147(1): 267-279, 2021 01.
Article em En | MEDLINE | ID: mdl-32941940
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Mutação de Sentido Incorreto / Ubiquitinação / Proteína 3 que Contém Domínio de Pirina da Família NLR Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans / Infant / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Mutação de Sentido Incorreto / Ubiquitinação / Proteína 3 que Contém Domínio de Pirina da Família NLR Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans / Infant / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article