Determination of extent of PEGylation using denaturing capillary isoelectric focussing.

Minshull, Thomas C; Wood, Amanda; Roberts, David; Hallam, Christine; Lewis, Joshua; Orekoya, Adetola; Gervais, David

Minshull, Thomas C; Wood, Amanda; Roberts, David; Hallam, Christine; Lewis, Joshua; Orekoya, Adetola; Gervais, David.

Afiliação

Minshull TC; Immunocore Limited, Milton Park, Abingdon, Oxfordshire, OX14 4RY, United Kingdom.
Wood A; Biomolecular Formulation and Characterisation Sciences, UCB, Slough, SL1 3WE, United Kingdom.
Roberts D; Porton Biopharma Limited, Manor Farm Road, Porton Down, Salisbury, Wiltshire, SP4 0JG, United Kingdom.
Hallam C; Porton Biopharma Limited, Manor Farm Road, Porton Down, Salisbury, Wiltshire, SP4 0JG, United Kingdom.
Lewis J; Porton Biopharma Limited, Manor Farm Road, Porton Down, Salisbury, Wiltshire, SP4 0JG, United Kingdom.
Orekoya A; LondonEnergy, EcoPark, Advent Way, London, N18 3AG, United Kingdom.
Gervais D; Porton Biopharma Limited, Manor Farm Road, Porton Down, Salisbury, Wiltshire, SP4 0JG, United Kingdom. Electronic address: dave.gervais@portonbiopharma.com.

Anal Biochem ; 611: 113953, 2020 12 15.

Article em En | MEDLINE | ID: mdl-32946834

Assuntos

Asparaginase; Proteínas de Bactérias; Dickeya chrysanthemi/enzimologia; Polietilenoglicóis; Asparaginase/análise; Asparaginase/química; Proteínas de Bactérias/análise; Proteínas de Bactérias/química; Eletroforese Capilar; Focalização Isoelétrica; Polietilenoglicóis/análise; Polietilenoglicóis/química

Palavras-chave

Capillary electrophoresis; Capillary isoelectric focussing; Erwinial-asparaginase; PEGylation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polietilenoglicóis / Asparaginase / Proteínas de Bactérias / Dickeya chrysanthemi Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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