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Inactivation of ApoC3 by CRISPR/Cas9 Protects Against Atherosclerosis in Hamsters.
Guo, Mengmeng; Xu, Yitong; Dong, Zhao; Zhou, Zihao; Cong, Nathan; Gao, Mingming; Huang, Wei; Wang, Yuhui; Liu, George; Xian, Xunde.
Afiliação
  • Guo M; Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Peking University, Beijing, China (M.G., Z.D., Z.Z., N.C., W.H., Y.W., G.L., X.X.).
  • Xu Y; Laboratory of Lipid Metabolism, Institute of Basic Medicine, Hebei Medical University, Shijiazhuang, China (Y.X., M.G.).
  • Dong Z; Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Peking University, Beijing, China (M.G., Z.D., Z.Z., N.C., W.H., Y.W., G.L., X.X.).
  • Zhou Z; Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Peking University, Beijing, China (M.G., Z.D., Z.Z., N.C., W.H., Y.W., G.L., X.X.).
  • Cong N; Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Peking University, Beijing, China (M.G., Z.D., Z.Z., N.C., W.H., Y.W., G.L., X.X.).
  • Gao M; Laboratory of Lipid Metabolism, Institute of Basic Medicine, Hebei Medical University, Shijiazhuang, China (Y.X., M.G.).
  • Huang W; Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Peking University, Beijing, China (M.G., Z.D., Z.Z., N.C., W.H., Y.W., G.L., X.X.).
  • Wang Y; Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Peking University, Beijing, China (M.G., Z.D., Z.Z., N.C., W.H., Y.W., G.L., X.X.).
  • Liu G; Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Peking University, Beijing, China (M.G., Z.D., Z.Z., N.C., W.H., Y.W., G.L., X.X.).
  • Xian X; Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Peking University, Beijing, China (M.G., Z.D., Z.Z., N.C., W.H., Y.W., G.L., X.X.).
Circ Res ; 127(11): 1456-1458, 2020 11 06.
Article em En | MEDLINE | ID: mdl-32951534
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Terapia Genética / Deleção de Genes / Aterosclerose / Apolipoproteína C-III / Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas / Sistemas CRISPR-Cas / Proteína 9 Associada à CRISPR Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Terapia Genética / Deleção de Genes / Aterosclerose / Apolipoproteína C-III / Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas / Sistemas CRISPR-Cas / Proteína 9 Associada à CRISPR Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article