N-terminally truncated nucleocapsid protein of SARS-CoV-2 as a better serological marker than whole nucleocapsid protein in evaluating the immunogenicity of inactivated SARS-CoV-2.

Yue, Lei; Cao, Han; Xie, Tianhong; Long, Runxiang; Li, Hua; Yang, Ting; Yan, Min; Xie, Zhongping

Yue, Lei; Cao, Han; Xie, Tianhong; Long, Runxiang; Li, Hua; Yang, Ting; Yan, Min; Xie, Zhongping.

Afiliação

Yue L; The Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, Yunnan, China.
Cao H; The Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, Yunnan, China.
Xie T; The Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, Yunnan, China.
Long R; The Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, Yunnan, China.
Li H; The Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, Yunnan, China.
Yang T; The Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, Yunnan, China.
Yan M; Department of Microbiology and Immunology, Kunming Medical University, Kunming, Yunnan, China.
Xie Z; The Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, Yunnan, China.

J Med Virol ; 93(3): 1732-1738, 2021 03.

Article em En | MEDLINE | ID: mdl-32965677

Assuntos

Anticorpos Antivirais/imunologia; Vacinas contra COVID-19/imunologia; Proteínas do Nucleocapsídeo de Coronavírus/imunologia; SARS-CoV-2/imunologia; Glicoproteína da Espícula de Coronavírus/imunologia; Vacinas de Produtos Inativados/imunologia; Animais; COVID-19/prevenção & controle; Proteínas do Nucleocapsídeo de Coronavírus/genética; Humanos; Camundongos; Camundongos Endogâmicos BALB C; Fosfoproteínas/genética; Fosfoproteínas/imunologia; Coelhos; SARS-CoV-2/genética; Deleção de Sequência/genética; Deleção de Sequência/imunologia; Glicoproteína da Espícula de Coronavírus/genética

Palavras-chave

N-terminally truncated NP; SARS-CoV-2; protein expression and purification; sensitivity

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vacinas de Produtos Inativados / Glicoproteína da Espícula de Coronavírus / Proteínas do Nucleocapsídeo de Coronavírus / Vacinas contra COVID-19 / SARS-CoV-2 / Anticorpos Antivirais Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google