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Recent progress of 1,1-difunctionalization of olefins.
Yang, Shuang; Chen, Yuhang; Ding, Zhenhua.
Afiliação
  • Yang S; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China. zhding@cpu.edu.cn.
  • Chen Y; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China. zhding@cpu.edu.cn.
  • Ding Z; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China. zhding@cpu.edu.cn.
Org Biomol Chem ; 18(36): 6983-7001, 2020 09 23.
Article em En | MEDLINE | ID: mdl-32966541
Olefins are a very important class of compounds and broadly used in the construction of various synthetic building blocks and practical industrial production. The difunctionalization of olefins provides one of the most powerful methods for the C-C or C-X bond formation with a rapid increase of the molecular complexity and synthetic value economically and effectively. Compared with the vigorous growth and abundant achievements of 1,2-difunctionalization of olefins, 1,1-difunctionalization is a relatively emerging and inadequately exploited research direction, despite being tremendously attractive from synthetic perspectives. In this minireview, we provide a brief overview of the advancements of 1,1-difunctionalization of olefins in the past twenty years, and prospects of future developments.

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article